Toulouse-Lautrec syndrome. I had never seen a case before, but I had heard it described. Named for its most famous sufferer (who did not yet exist, I reminded myself), it was a degenerative disease of bone and connective tissue. Victims often appeared normal, if sickly, until their early teens, when the long bones of the legs, under the stress of bearing a body upright, began to crumble and collapse upon themselves.