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That Jesus had brothers is, despite the Catholic doctrine of his mother Mary's perpetual virginity, virtually indisputable. It is a fact attested to repeatedly by both the gospels and the letters of Paul. Even Josephus references Jesus's brother James, who would become the most important leader of the early Christian church after Jesus's death. There is no rational argument that can be made against the notion that Jesus was part of a large family that included at least four brothers who are named in the gospels--James, Joseph, Simon, and Judas--and an unknown number of sisters who, while mentioned in the gospels, are unfortunately not named.