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The humans who domesticated animals were the first to fall victim to the newly evolved germs, but those humans then evolved substantial resistance to the new diseases. When such partly immune people came into contact with others who had had no previous exposure to the germs, epidemics resulted in which up to 99 percent of the previously unexposed population was killed. Germs thus acquired ultimately from domestic animals played decisive roles in the European conquests of Native Americans, Australians, South Africans, and Pacific islanders.