"So you attempt what De Bruik attempted, in her Free Radical Binds to Macromolecule." "We all attempt what De Bruik attempted, in one way or another." In Free Radical De Bruik had represented the macromolecule, an RNA strand, as a passacaglia, a ground base repeated again and again, in patterns of four that alternated regularly. This was a simple icon, a metaphor in which the repeated ground base stood for the repeated proteins in the RNA; fine. And the free radical's part was a test for any trumpet player."