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667aa5b Logically, when the amygdala wants to mobilize a behavior--say, fleeing--it talks to the frontal cortex, seeking its executive approval. But if sufficiently aroused, the amygdala talks directly to subcortical, reflexive motor pathways. Again, there's a trade-off--increased speed by bypassing the cortex, but decreased accuracy. Thus the input shortcut may prompt you to see the cell phone as a gun. And the output shortcut may prompt you to pu.. Robert M. Sapolsky
0019e47 Something roughly akin to love is needed for proper biological development, and its absence is among the most aching, distorting stressors that we can suffer. Robert M. Sapolsky
9738a89 If you have to boil this book down to a single phrase, it would be "it's complicated." -- human-behavior neuroscience environment psychology Robert M. Sapolsky
0d6c818 The final misconception is that evolution is "just a theory." I will boldly assume that readers who have gotten this far believe in evolution. Opponents inevitably bring up that irritating canard that evolution is unproven, because (following an unuseful convention in the field) it is a "theory" (like, say, germ theory). Evidence for the reality of evolution includes: Numerous examples where changing selective pressures have changed gene fr.. Robert M. Sapolsky
caaf0e2 Beginning in the early 1980s, various researchers, including myself, showed that this "glucocorticoid neurotoxicity" was not just a pharmacological effect, but was relevant to normal brain aging in the rat. Collectively, the studies showed that lots of glucocorticoid exposure (in the range seen during stress) or lots of stress itself would accelerate the degeneration of the aging hippocampus. Conversely, diminishing glucocorticoid levels (b.. Robert M. Sapolsky
97cb26f Major depression. As will be detailed in chapter 14, major depression is utterly intertwined with prolonged stress, and this connection includes elevated glucocorticoid levels in about half the people with major depression. Yvette Sheline of Washington University and others have shown that prolonged major depression is, once again, associated with a smaller hippocampus. The more prolonged the history of depression, the more volume loss. Fur.. Robert M. Sapolsky
67653bb In other cases the challenge is to appreciate how, though human physiology resembles that of other species, we use the physiology in novel ways. Robert M. Sapolsky
f33a7c7 If people around you smell scared, your brain tilts toward concluding that you are too.25 Robert M. Sapolsky
f45f26e acute stress strengthens connectivity between the frontal cortex and motoric areas, while weakening frontal-hippocampal connections; the result is decision making that is habitual, rather than incorporating new information. Robert M. Sapolsky
7e4846e It is the ambiguity of violence, that we can pull a trigger as an act of hideous aggression or of self-sacrificing love, that is so challenging. Robert M. Sapolsky
d901158 The shape of women's faces changes subtly during their ovulatory cycle, and men prefer female faces at the time of ovulation. Robert M. Sapolsky
57a55ce The human olfactory system is atrophied; roughly 40 percent of a rat's brain is devoted to olfactory processing, versus 3 percent in us. Robert M. Sapolsky
9590c95 If people around you smell scared, your brain tilts toward concluding that you are too. Robert M. Sapolsky
7f181d7 In other words, pain makes aggressive people more aggressive, while doing the opposite to unaggressive individuals.27 Robert M. Sapolsky
46c49e5 when the frontal cortex labors hard on some cognitive task, immediately afterward individuals are more aggressive and less empathic, charitable, and honest. Robert M. Sapolsky
5d39fd3 And behavior is altered by "situational labels"--call the game the "Wall Street Game," and people become less cooperative. Calling it the "Community Game" does the opposite." Robert M. Sapolsky
23f408e If they're told, "The drug has a 95 percent survival rate," people, including doctors, are more likely to approve it than when told, "The drug has a 5 percent death rate." Robert M. Sapolsky
9d20b10 The cognitive capacities of near-term fetuses are even more remarkable. For example, fetuses can distinguish between two pairs of nonsense syllables ("biba" versus "babi"). How do you know? Get this--Mom says "Biba, biba, biba" repeatedly while fetal heart rate is monitored. "Boring (or perhaps lulling)," thinks the fetus, and heart rate slows. Then Mom switches to "babi." If the fetus doesn't distinguish between the two, heart rate deceler.. Robert M. Sapolsky
1f01fc7 The opposite of love is not hate; its opposite is indifference." The biologies of strong love and strong hate are similar in many ways, as we'll see." Robert M. Sapolsky
46efdc9 If you pay lots of attention to where boundaries are, you pay less attention to complete pictures. Robert M. Sapolsky
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