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d73157d In the bipolar patients we have studied, there is a significantly increased number of small areas of focal signal hyperintensities [areas of increased water concentration] suggestive of abnormal tissue. These are what neurologists sometimes refer to as 'unidentified bright objects,' or UBOs. Kay Redfield Jamison
4219ea1 I also started giving Christmas lectures to the house staff and clinic staff that focused on music written by composers who had experienced severe depression or manic-depressive illness. These informal lectures became the basis for a concert that a friend of mine, a professor of music at UCLA, and I subsequently produced in 1985 with the Los Angeles Philharmonic. In an attempt to raise public awareness about mental illness, Kay Redfield Jamison
9edc869 manic-depressive illness, we proposed to the executive director of the Philharmonic a program based on the lives and music of several composers who had suffered from the illness, including Robert Schumann, Hector Berlioz, and Hugo Wolf. Kay Redfield Jamison
27c33e1 knew better than to assume a straight shot at happiness: If we see a light at the end of the tunnel, he said, it's the light of an oncoming train. Kay Redfield Jamison
3df236c It is the history of our kindnesses that alone makes this world tolerable," wrote Robert Louis Stevenson. "If it were not for that, for the effect of kind words, kind looks, kind letters ... I should be inclined to think our life a practical jest in the worst possible spirit." Kay Redfield Jamison
cabe69e His wife maintains she can tell whether or not Jim is in the house simply by the amount of energy she feels in the air. But Kay Redfield Jamison
dc0f965 Mogens Schou, a Danish psychiatrist who, more than anyone, is responsible for the introduction of lithium as a treatment for manic-depressive illness, Kay Redfield Jamison
f53c58d John Cade's article about the use of lithium in acute mania first appeared in 1949, in an obscure Australian medical journal, Kay Redfield Jamison
63bb372 It did the kind of lasting damage that only something that cuts so quick and deep to the heart can do. Kay Redfield Jamison
a7b5e30 We all build internal sea walls to keep at bay the sadnesses of life and the often overwhelming forces within our minds. In whatever way we do this - through love, work, family, faith, friends, denial, alcohol, drugs, or medication - we build these walls, stone by stone, over a lifetime. One of the most difficult problems is to construct these barriers of such a height and strength that one has a true harbor, a sanctuary away from crippling.. Kay Redfield Jamison
b24fcc3 manic-depressive illness can confer advantages on both the individual and society. The disease, in both its severe and less severe forms, appears to convey its advantages not only through its relationship to the artistic temperament and imagination, but through its influence on many eminent scientists, as well as business, religious, military, and political leaders. Subtler effects--such as those on personality, thinking style, and energy--.. Kay Redfield Jamison
b159fd4 Schubert's posthumous Piano Sonata in B-flat, D. 960. Its Kay Redfield Jamison
a0cf32f Mania is a strange and driving force, a destroyer, a fire in the blood. Kay Redfield Jamison
647553f Now and again she would break in with "Yes, yes, that's very interesting," "Of course you can," or "Had you thought of ...?" Never, but never, was there an "I don't think that's very practical" or "Why don't you just wait and see how it goes?" -- Kay Redfield Jamison
47ebc7c He, like my father, had a deep love for natural science, and he would discuss at length how physics, philosophy, and mathematics were, each in their own ways, jealous mistresses who required absolute passion and attention. Kay Redfield Jamison
58e1156 Navy Cotillion was where officers' children were supposed to learn the fine points of manners, dancing, white gloves, and other unrealities of life. It also was where children were supposed to learn, as if the preceding fourteen or fifteen years hadn't already made it painfully clear, that generals outrank colonels who, in turn, outrank majors and captains and lieutenants, and everyone, but everyone, outranks children. Within the ranks of c.. Kay Redfield Jamison
5e39ed8 Naquela noite, enquanto esperava (bordando, vendo a neve cair, ouvindo Chopin e Elgar) que meu ingles apaixonado e instavel aparecesse, eu de repente me conscientizei de como a musica me parecia clara e tocante; como era de uma beleza extrema e melancolica o fato de eu observar a neve e esperar por ele. Eu estava sentindo mais beleza, mas tambem mais tristeza de verdade. Quando ele surgiu - elegante, acabando de chegar de um jantar de cerim.. Kay Redfield Jamison
8fef797 But, ineffably, psychotherapy heals. It makes some sense of the confusion, reins in the terrifying thoughts and feelings, returns some control and hope and possibility of learning from it all. Pills cannot, do not, ease one back into reality; they only bring one back headlong, careening, and faster than can be endured at times. Psychotherapy is a sanctuary; it is a battleground; it is a place I have been psychotic, neurotic, elated, confuse.. Kay Redfield Jamison
7c6cdfa But it has been precisely that persevering steadiness of my mother, her belief in seeing things through, and her great ability to love and learn, listen and change, that helped keep me alive through all of the years of pain and nightmare that were to come. Kay Redfield Jamison
c994ffa I was one of many who owed their lives to the black circles and squares in Schou's family tree. Kay Redfield Jamison
deba1e8 As his psychotherapist for years, I had been privy to his dreams and fears, hopeful and then ruined relationships, grandiose and then shattered plans for the future. I had seen his remarkable resilience, personal courage, and wit; I liked and respected him enormously. But I also had been increasingly frustrated by his repeated refusals to take medication. I could, from my own experience, understand his concerns about taking lithium, but onl.. Kay Redfield Jamison
e6519f5 Humor and absorption on friends'faces are replaced by fear and concern. Kay Redfield Jamison
24dd421 He was a psychiatrist, as well as a warm, whimsical, and witty man who had a mind like a cluttered attic. Kay Redfield Jamison
feb4681 Fire, by its nature, both creates and destroys. Kay Redfield Jamison
2cedd9e For someone with my cast of mind and mood, medication is an integral element of this wall: without it, I would be constantly beholden to the crushing movements of a mental sea; I would, unquestionably, be dead or insane. Kay Redfield Jamison
d7566ec Far too many doctors--many of them excellent physicians--commit suicide each year; one recent study concluded that, until quite recently, the United States lost annually the equivalent of a medium-sized medical school class from suicide alone. Most physician suicides are due to depression or manic-depressive illness, both of which are eminently treatable. Physicians, unfortunately, not only suffer from a higher rate of mood disorders than t.. Kay Redfield Jamison
8d6c8c0 I had gotten a Ph.D., and I was beginning to understand Bob Dylans lines "Twenty years of schoolin' and they put you on the day shift." Kay Redfield Jamison
0efdbbf Do we risk making the world a blander, more homogenized place if we get rid of the genes for manic-depressive illness Kay Redfield Jamison
9a4c61f before you can conquer a beast you first must make it beautiful. Kay Redfield Jamison
224234f Much like crossing the Bay Bridge when there is a storm over the Chesapeake, one may be terrified to go forward, but there is no question of going back. Kay Redfield Jamison
a62efad You never knew those caves were there. It will never end, for madness carves its own reality. Kay Redfield Jamison
82b043d This polarization of two clinical states flies in the face of everything that we know about the cauldronous, fluctuating nature of manic-depressive illness; it ignores the question of whether mania is, ultimately, simply an extreme form of depression; and it minimizes the importance of mixed manic-and-depressive states, conditions that are common, extremely important clinically, and lie at the heart of many of the critical theoretical issue.. Kay Redfield Jamison
89a1d2b for manics anyway, mania is a natural extension of the economy. Kay Redfield Jamison
248d60d Far more important, they took me and my interests very seriously. They never tried to discourage me from becoming a doctor, even though it was an era that breathed, If woman, be a nurse. Kay Redfield Jamison
068a40f I focused on the questions and stopped seeing the body. As has been true a thousand times since, my curiosity and temperament had taken me to places I was not really able to handle emotionally, but the same curiosity, and the scientific side of my mind, generated enough distance and structure to allow me to manage, deflect, reflect, and move on. Kay Redfield Jamison
c44f1ac It would be impossible for me to convince you that the gray square labeled A is identical in brightness to the square labeled B. Keith Payne
d22e147 Rachel lay in bed, staring at a ceiling she couldn't see in the darkness. Her brother, Jonathan, was a few feet away; his breathing, regular and deep. Keith Nixon
52e8bb9 I for many years after my initial diagnosis was reluctant to take my medications as prescribed. Why was I so unwilling? Why did it take having to go through more episodes of mania, followed by long suicidal depressions, before I would take lithium in a medically sensible way? Some of my reluctance, no doubt, stemmed from a fundamental denial that what I had was a real disease. This is a common reaction that follows, rather counter-intuitive.. Kay Redfield Jamison
02ad167 high altitude coupled with rigorous exercise can raise lithium levels. I became completely disoriented and totally incapable of navigating my way down the mountain. Kay Redfield Jamison
1bc25a1 Reading, which had been at the heart of my intellectual and emotional existence, Kay Redfield Jamison
18044e6 because the California commitment code is designed more for the well-being of lawyers than of patients, it would have been relatively easy for me to talk my way out of an involuntary commitment. Kay Redfield Jamison
7b16411 Somehow, like so many people who get depressed, we felt our depressions were more complicated and existentially based than they actually were. Antidepressants might be indicated for psychiatric patients, for those of weaker stock, but not for us. It was a costly attitude; our upbringing and pride held us hostage. Kay Redfield Jamison
7f3b71c The endless questioning finally ended. My psychiatrist looked at me, there was no uncertainty in his voice. "Manic-depressive illness." I admired his bluntness. I wished him locusts on his lands and a pox upon his house. Silent, unbelievable rage. I smiled pleasantly. He smiled back. The war had just begun." Kay Redfield Jamison
5888ffe The humor, however, was a bit more in the recounting than in the actual living through it. Unfortunately, this resistance to taking lithium is played out in the lives of tens of thousands of patients every year. Kay Redfield Jamison